イケダ マリ   Mari Ikeda   池田　茉莉    所属   千葉工業大学  工学部 教育センター（工学部）    職種   教授
言語種別	英語
発行・発表の年月	2021/07
形態種別	学術雑誌
査読	査読あり
標題	Cosmosen: Octa-Armed 24-Membered Cyclic Octaamine Synthesized from a Byproduct in the Preparation of 4-Benzyl-2,6-dioxocyclen.
執筆形態	共著
掲載誌名	The Journal of Organic Chemistry
掲載区分	国外
出版社・発行元	American Chemical Society
巻・号・頁	86(14),pp.9847-9853
著者・共著者	Ju Huiyeong, Iwase Miki, Sako Hikari, Horita Hiroki, Koike Shiori, Lee Eunji, Ikeda Mari, Kuwahara Shunsuke, Habata Yoichi*
概要	The synthesis of an octa-armed 24-membered cyclic octaamine (1) is reported. When 4-benzyl-1,4,7,10-tetraazacyclododecane-2,6-dione (3a) was prepared by the reaction of diethylenetriamine with diethyl N-benzyliminodiacetate (2), a dimeric macrocycle (3b) was obtained as a byproduct in a 5% yield. An octa-armed 24-membered cyclic octaamine (1), named Cosmosen, was prepared via the reductive amination and reduction of 3b. The binding constants for the 1:1 and 2:1 (Ag+/1) complexation of 1 were estimated to be ca. 7.9 and 13.9, respectively, by titration experiments using UV-vis spectrometry in methanol and chloroform (v/v, 9:1) solutions at 298 K.
DOI	10.1021/acs.joc.1c00737
ISSN	1520-6904
PMID	34098715