ネモト　ナオキ   Naoki Nemoto   根本　直樹    所属   千葉工業大学  先進工学部 生命科学科    千葉工業大学  工学研究科 工学専攻    千葉工業大学  先進工学研究科 生命科学専攻    職種   教授
言語種別	日本語
発行・発表の年月	2022/12
形態種別	学術雑誌
査読	査読あり
標題	PGLN: A newly identified amino phosphoglycolipid species in Thermus thermophilus HB8.
執筆形態	共著
掲載誌名	Biochemistry and biophysics reports
掲載区分	国外
巻・号・頁	32,101377頁
担当区分	筆頭著者,責任著者
著者・共著者	Nemoto Naoki, Kawaguchi Masahiko, Yura Kei, Shimada Haruo, Bessho Yoshitaka
概要	Thermus thermophilus has several minor lipid molecules with structures that have not been described yet. In this study, we identified a new lipid molecule in T. thermophilus HB8 with an amino group at the polar head, by detecting lipid spots with HPTLC and mass spectrometry. The structure of the lipid resembles an amino sugar phospholipid, except for the glucosamine that lacks an acetyl group. We named this amino phosphoglycolipid PGLN, and proposed its synthetic pathway from a precursor, phosphatidyl-glyceric alkylamine. The primary amine structure of PGLN may contribute to high temperature adaptation through electrostatic interactions between the head groups.
DOI	10.1016/j.bbrep.2022.101377
ISSN	2405-5808
PMID	36345289