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シバタ ミツヒロ
SHIBATA MITSUHIRO
柴田 充弘 所属 千葉工業大学 工学部 応用化学科 千葉工業大学 工学研究科 工学専攻 千葉工業大学 工学研究科 応用化学専攻 職種 教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2015/01 |
| 形態種別 | 学術雑誌 |
| 査読 | 査読あり |
| 標題 | Fibroblast cell proliferation on photo-cured trehalose cinnamoyl ester thin films |
| 執筆形態 | 共著 |
| 掲載誌名 | Journal of Bioactive and Compatible Polymers |
| 掲載区分 | 国外 |
| 出版社・発行元 | SAGE Publications |
| 巻・号・頁 | 30(1),pp.87-98 |
| 著者・共著者 | Shinya Yano, Naozumi Teramoto, Rikako Miyamoto, Eiichi Nakajima, Kazuaki Hashimoto, Mitsuhiro Shibata |
| 概要 | Two trehalose cinnamoyl esters (TCs) with different degrees of substitution were coated on glass plates by a dip-coating method. Photocuring of the TCs was confirmed by UV-Vis spectral changes. The cell proliferation on photo-cured TCs (cTCs) was investigated using 3T3 Swiss Albino mouse embryo fibroblasts. The results of the cell proliferation assay revealed that cTCs with higher degrees of substitution promoted the cell proliferation compared with a polystyrene culture plate and cTCs with lower degrees of substitution. The contact angle of cTCs with higher degrees of substitution was much higher than that of the polystyrene culture plate, and it is out of the range known to be suitable for cell adhesion. Nevertheless, the cell unexpectedly grew best on cTCs with higher degrees of substitution. Fibronectin binding assay was carried out using fluorescent probe-modified fibronectin, and more fibronectin was adsorbed onto cTCs than a polystyrene culture plate. |
| DOI | 10.1177/0883911514558012 |
| ISSN | 0883-9115 |