クマタニ　アキチカ   Akichika Kumatani   熊谷　明哉    所属   千葉工業大学  工学部 電気電子工学科    千葉工業大学  工学研究科 工学専攻    職種   教授
言語種別	英語
発行・発表の年月	2017
形態種別	学術雑誌
査読	査読あり
標題	3D electrochemical and ion current imaging using scanning electrochemical-scanning ion conductance microscopy
執筆形態	共著
掲載誌名	Physical Chemistry Chemical Physics
掲載区分	国外
出版社・発行元	ROYAL SOC CHEMISTRY
巻・号・頁	19(39),pp.26728-26733
著者・共著者	Yasufumi Takahashi,Hiroki Ida,Yoshiharu Matsumae,Hirokazu Komaki,Yuanshu Zhou,Akichika Kumatani,Makoto Kanzaki,Hitoshi Shiku,Tomokazu Matsue
概要	Local cell-membrane permeability and ionic strength are important factors for maintaining the functions of cells. Here, we measured the spatial electrochemical and ion concentration profile near the sample surface with nanoscale resolution using scanning electrochemical microscopy (SECM) combined with scanning ion-conductance microscopy (SICM). The ion current feedback system is an effective way to control probe-sample distance without contact and monitor the kinetic effect of mediator regeneration and the chemical concentration profile. For demonstrating 3D electrochemical and ion concentration mapping, we evaluated the reaction rate of electrochemical mediator regeneration on an unbiased conductor and visualized inhomogeneous permeability and the ion concentration 3D profile on a single fixed adipocyte cell surface.
DOI	10.1039/c7cp05157c
ISSN	1463-9076/1463-9084
PMID	28951914